From Peter Leugner:
Install the latest wine from www.winehq.com (or emerge wine, apt-get wine or whatever).
Install Notes 6.51 under Windows.
Copy the the Notes directory to ~/.wine/fake_windows/program files.
Copy mfc42.dll and msvcp60.dll from Windows to ~/.wine/fake_windows/windows/system
Type
wine "c:\program files\lotus\notes\nlnotes.exe"
In Designer you also can edit and compile Java Agents now, I couldn't do that with R5 on wine.